Male aging Menopause and Testosterone

Male aging Menopause and Testosterone

Male aging Menopause and Testosterone

Male menopause requires an understanding of two important Factors: Aging and Testosterone. It is also important to treat or manage in a condition where aging progresses and function deteriorates, but rather, you should pay attention to changes in your body and body functions when you are healthy.

Do men have menopause? As women, the beginning is not clear, but I think there is. Men’s life expectancy is prolonged and the desire to be active, including economic activities, increases in an atmosphere that tries to overcome economic difficulties by exerting their abilities as little as possible. Menopause is a growing tendency to recognize menopause. Men’s menopause does not have menopause, which is a time when female hormones are dramatically reduced like women and the transition from fertility to menopause. There is this. Women have a dramatic distinction between menopause, that is, ovulation that produces the ovaries and the accompanying female hormone secretion and stopping bleeding. In addition, in women, it comes quickly enough to say that it is an instant, while in men it comes slowly in various ways. Men come about ten years later than women.

Facts about Make Testosterone

Studies to date show that the decrease in the male hormone testosterone due to aging is relatively well known. According to the results of a large study 11 of men aged 39-70 years old, testosterone levels decrease by 1.0-1.2% each year. In addition, other studies also demonstrated a decrease in serum testosterone with aging, which was about 15-20 ng/dl every 10 years.


Various symptoms appear in men as the male hormone decreases. Fatigue, weakness, decreased muscle strength and muscle mass, increased body fat, decreased hemoglobin, decreased libido, erectile dysfunction, infertility, osteoporosis, hot flashes, anxiety, anxiety, depression, insomnia, decreased motivation, and decreased memory and concentration.

How to Take testosterone supplementation

There are three methods of testosterone supplementation: injection, oral drug, and patch. 

Injection
is a method of intramuscular injection once every 3-4 weeks. The maximum concentration is reached within 72 hours after injection and then gradually decreases over several hours. The advantage is that sufficient blood testosterone concentration can be reached and this is maintained for weeks. However, this method cannot cause fluctuations in intraday blood concentrations of hormones, which are normal biological rhythms, and abnormally higher testosterone concentrations than physiological doses (roller coaster effect) and breast pain may occur, and there is a disadvantage of injection.

Oral drug
In the past, it was an edible drug because it had hepatotoxicity, so it was not used a lot, but the recently used fat-soluble drug is an edible drug. However, high blood concentrations above physiological concentrations may be caused, and since it is absorbed through the lymphatic system, it must be taken with meals, and because the half-life is short, it must be taken twice a day, and sometimes causes indigestion.

Transdermal Patch
This is the method to attach to the scrotum, a method to apply to the skin, etc. have been developed. Compared to injection drugs and oral drugs, the blood level most similar to the physiological blood concentration of male hormones It is recommended as the most ideal method because it can make concentration and does not cause discomfort or indigestion of injection, but it can cause skin irritation and hypersensitivity reactions and have a disadvantage in that their preference is lower than injections or oral drugs.

Changes in the Body During Male Menopause
There are many changes in the body during male menopause, and the important things are as follows. The number of hairs decreases. Memory decreases after the twenties. However, concentration, vocabulary, and expressiveness do not change significantly. In the late fifties, the eardrum thickens and the inside of the ear shrinks, reducing the perception of treble or high frequencies. Presbyopia comes. Heart and lung function decline, endurance decreases. Fat in the body increases, giving relatively muscle.

These changes result in a decrease in endurance and all other functions. Even at the age of fifty or seventy, sexual desire is felt enough, but the frequency of sex usually decreases, but individual differences are large. However, as the erection ability decreases, the probability of impotence increases.

Among the ways to slow male menopause, the most active in the administration of androgens, a male hormone. However, there are side effects such as prostate cancer, suppression of semen production, and reduction of high-density lipoprotein cholesterol, which is beneficial to our body, so try carefully according to the prescription of a specialist. Therefore, the method that is more emphasized is not excessive stability and healthy life including sexual life. Appropriate exercise and generous nutrition can also help. It will be more helpful if you take these methods step by step from a young age. Of course, the first thing to do is to check whether it is natural aging or whether it is a pathological condition caused by primary causes such as drugs, obesity, hypothyroidism, alcohol consumption, diabetes, and testicular damage. If it is caused by a disease, you should be actively treated.

Male Testosterone Muscle

In addition, male Testosterone increases the synthesis of muscle proteins, resulting in muscle hypertrophy. However, recent observations suggest that the increase in muscle protein synthesis occurs as a secondary result, not as a sole or main mechanism by which male Testosterone induce muscle hypertrophy. The molecular mechanism that regulates muscle hypertrophy by androgens is still unknown. The effect of male Testosterone on muscles is regulated by several factors such as genetic background, secretion status of growth hormone, nutrition, cytokines, thyroid hormone, and adrenal corticosteroid. Male Testosterone also affects muscle function through effects on neuromuscular transmission.

Male Testosterone with Fat Metabolism

Male Testosterone has a distinct effect on fat metabolism. The percentage of body fat is higher in men with hypogonadism than in normal people. Long-term studies of male hormone supplementation therapy in the elderly have consistently shown a reduction in fat mass. In middle-aged men with visceral obesity, male hormone supplementation therapy improves insulin sensitivity and reduces blood sugar and blood pressure. In addition to abdominal fat, a decrease in muscle-to-muscular fat is also associated with high doses of testosterone.
Effects of androgenic on Men Testosterone with Age

While short-term androgenic use is relatively safe in young men with testosterone deficiency, the risk of long-term androgenic supplementation therapy in the elderly is still unclear.

Side effects of testosterone supplementation

Side effects of testosterone supplementation therapy include increased red blood cell count, incidence and worsening of apnea during sleep, and soreness or swelling when the breast is pressed. In addition, there are concerns about the possibility of progression of prostate cancer and atherosclerotic heart disease when used for a long time. There is a consensus that male Testosterone does not cause prostate cancer. There is also no significant relationship between serum testosterone levels and the risk of prostate cancer. However, prostate cancer is an androgen-dependent tumor, and taking androgens may promote tumor growth. Therefore, it is absolutely contraindicated in men with a history of prostate cancer. Elderly people are more likely to have asymptomatic prostate cancer that is detected only by microscopic examination and is not revealed. In this case, taking male Testosterone can lead to cancer. Based on these known facts, a long-term study is underway to determine the clinical benefits and risks of male hormone supplementation therapy in the elderly with low testosterone levels.

If the concentration of Hormones to the level of adolescents, will you become young? Decreased hormone levels are one of the many characteristics of old age. Usually, by the age of thirty, hormone levels begin to decrease, accelerating the aging process. By returning hormone levels to their younger levels, people can often experience similar hormone levels as they were younger. However, the effect is not a sign that aging has stopped and you are younger. Aging is a natural phenomenon that approaches us like rain. However, even if it is a natural physiological phenomenon, it is necessary to fix it first, as if the rainy season pours out or the house is old and the rain leaks, flooding measures, and catchment repairs must be hurried. However, I am cautious that over-finishing will ruin a house worth living.
Level of Male Hormone Testosterone
As levels of male hormone ( testosterone ) decrease, sexual urge (sexual desire) decreases. Blood flow to the penis decreases. Other changes include:

  • Decreased sensitivity of the penis
  • Decreased volume of fluid released during ejaculation
  • Reduced ejaculation notice
  • Orgasm without ejaculation
  • After orgasm, the penis stretches faster (constricts)
  • After orgasm, longer than before an erection can occur (refractory period)

Beginning around the age of 20, men’s testosterone (the main male hormone) production begins to decline by an average of 1 to 2% per year. The second half of life, when testosterone production decreases enough to cause distinct symptoms, is sometimes called male menopause or male menopause. However, the gradual hormonal decline in men is very different from what women experience during menopause when female hormones is almost always declining rapidly in just a few years. The rate of decrease in testosterone varies considerably between men. Some men in their 70s have the same testosterone levels as the average man in their 30s.

Men of younger, older, or low testosterone have certain age-related traits, including decreased libido, decreased muscle mass, increased abdominal fat, slender bones that fracture easily ( osteoporosis ), decreased activity levels, and delayed thinking ability. And low blood count ( anemia ). Low testosterone levels also increase your risk of coronary artery disease.

Testosterone replacement therapy

Many men with normal testosterone levels are interested in taking testosterone to slow down or reverse the occurrence of the characteristic of low testosterone. However, currently, testosterone replacement therapy (TRT) is only recommended for men with hypogonadism, who have both low testosterone symptoms and abnormally low testosterone blood levels. The latest research has identified conflicting evidence suggesting an increased risk of heart attack and stroke in men receiving TRT.

Side effects of testosterone replacement therapy

While rare with testosterone treatment, certain side effects can occur, such as snoring, increased symptoms of urinary tract obstruction (usually caused by benign prostatic enlargement ), mood swings, acne, blood clots, and breast enlargement. Testosterone can sometimes cause the body to produce too many red blood cells, increasing the risk of various disorders such as blood clots and strokes.

Currently, testosterone treatment is not thought to affect the development or progression of prostate cancer. However, we do not fully understand this, so men should talk to their doctor about their risk of developing prostate cancer.

Follow-up observation of testosterone replacement therapy

Men who get testosterone need to be tested for changes in blood counts and prostate cancer every few months. These tests can detect cancer early, which increases your chances of getting cured. Some people with prostate cancer can get testosterone treatment, but they should see their doctor more frequently.

Conclusion

In summary, in order to be diagnosed with the male menopausal syndrome, the testosterone level measured in the blood must be lower than the normal level while having symptoms related to it. In addition, prior to entering male hormone supplementation therapy, evaluation of cardiovascular and prostate disease is necessary. Therefore, it is necessary to diagnose and manage an expert, and it is necessary to refrain from the diagnosis of the excessive male climacteric syndrome and unnecessary testosterone treatment.

 

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